Naivex 50 Mg Tablet

Product Description

Dolutegravir is indicated in combination with other anti-retroviral agents for the treatment of HIV-1 Infection in adults weighing more than 40 KG.

Administration Dolutegravir can be taken with or without food . In the presence of integrase class resistance, Dolutegravir should preferably be taken with food to enhance exposure.

Contraindications:-

Dolutegravir in contraindicated in

Hypersensitivity to the Dolutegravir or to any of the excipirnts of product

Combination with dofetilide due to the potential for increased dofetilide plasma concentration and the risk for serious and/or life-threatening events.

Overdose

There is limited experience with the over dosage in Dolutegravir. Limited experience of single higher doses revealed no specific symptoms or signs, apart from those listed as adverse reactions. then management in case of over dosage should be as clinically indicated or as recommended by the national poison center, where available. There is no Specific treatment for an overdose of Dolutegravir. if overdose occurs, the patient should be treated supportively with appropriate monitoring, as necessary. As Dolutegravir is highly bound plasma proteins, it is unlikely that it will be significantly removed by dialysis.